
Azelaic Acid 16 Calming Serum
- 16% Azelaic Acid refines texture & post-spot marks
- Niacinamide + Panthenol comfort stressed-looking skin
- Allantoin + Squalane hydrate & support the barrier
- Fast-absorbing, non-greasy — layers easily AM or PM
“My skin looks noticeably calmer and the redness around my cheeks has improved so much.”
Chloe V. ★★★★★“Lightweight, soothing, and never greasy. My post-spot marks already look softer.”
David L. ★★★★★“This leaves my skin feeling smooth and hydrated without causing irritation or dryness.”
Sarah M. ★★★★★“My skin looks noticeably calmer and the redness around my cheeks has improved so much.”
Chloe V. ★★★★★“Lightweight, soothing, and never greasy. My post-spot marks already look softer.”
David L. ★★★★★“This leaves my skin feeling smooth and hydrated without causing irritation or dryness.”
Sarah M. ★★★★★







How It Works
Glow in 3 simple steps
Cleanse & Tone
After cleansing and toning, apply 2–3 drops across the face.
Press In
Gently press the serum into the skin until absorbed, then moisturize.
Build Up Slowly
Use 2–3 evenings a week to start, then increase; finish with SPF by day.
Why This Serum Is Different
Calm, clear, comfortable skin
Calms Visible Redness
16% Azelaic Acid helps soothe redness caused by dryness.
Fades Post-Spot Marks
Softens the look of lingering marks and uneven texture.
Balances & Refines
Helps control excess oil for a clearer, more refined complexion.
Lightweight Hydration
Allantoin & Squalane hydrate and support the moisture barrier.
As Seen On Social
Real people, real glow
Loved By Hundreds
Real results, real reviews
Rated 4.8 / 5 by thousands of happy customers
Calmer, More Balanced Skin
After a few weeks my skin looks calmer and more balanced. The redness around my cheeks is less noticeable and my post-spot marks are softer. It absorbs quickly and never feels greasy.
Perfect For Uneven Texture
It feels soothing and layers perfectly under my moisturizer and sunscreen. My complexion looks smoother, clearer and more even where I usually get redness.
A New Nighttime Favorite
My skin feels hydrated and comfortable without the heavy feeling some serums leave. With regular use my post-spot marks look less prominent.
Softer Marks Fast
Lightweight, soothing and never greasy. My post-spot marks already look softer after consistent use.
No Irritation Or Dryness
This leaves my skin feeling smooth and hydrated without causing irritation or dryness, even as I built up usage.
Redness Way Down
My cheeks look so much calmer and more even. I introduced it slowly and my skin handles it beautifully.
Calmer, More Balanced Skin
After a few weeks my skin looks calmer and more balanced. The redness around my cheeks is less noticeable and my post-spot marks are softer. It absorbs quickly and never feels greasy.
Perfect For Uneven Texture
It feels soothing and layers perfectly under my moisturizer and sunscreen. My complexion looks smoother, clearer and more even where I usually get redness.
A New Nighttime Favorite
My skin feels hydrated and comfortable without the heavy feeling some serums leave. With regular use my post-spot marks look less prominent.
Softer Marks Fast
Lightweight, soothing and never greasy. My post-spot marks already look softer after consistent use.
No Irritation Or Dryness
This leaves my skin feeling smooth and hydrated without causing irritation or dryness, even as I built up usage.
Redness Way Down
My cheeks look so much calmer and more even. I introduced it slowly and my skin handles it beautifully.
Calmer, More Balanced Skin
After a few weeks my skin looks calmer and more balanced. The redness around my cheeks is less noticeable and my post-spot marks are softer. It absorbs quickly and never feels greasy.
Perfect For Uneven Texture
It feels soothing and layers perfectly under my moisturizer and sunscreen. My complexion looks smoother, clearer and more even where I usually get redness.
A New Nighttime Favorite
My skin feels hydrated and comfortable without the heavy feeling some serums leave. With regular use my post-spot marks look less prominent.
Softer Marks Fast
Lightweight, soothing and never greasy. My post-spot marks already look softer after consistent use.
No Irritation Or Dryness
This leaves my skin feeling smooth and hydrated without causing irritation or dryness, even as I built up usage.
Redness Way Down
My cheeks look so much calmer and more even. I introduced it slowly and my skin handles it beautifully.
Everything You Need To Know
The Details

Product Details
Medicube Azelaic Acid 16 Calming Serum is a concentrated facial serum formulated to improve the appearance of visible redness caused by dryness, uneven-looking texture, and lingering post-spot marks. The lightweight formula combines 16% Azelaic Acid with Niacinamide, Panthenol, Allantoin, and Squalane to soothe, hydrate, and support a smoother, clearer-looking complexion without a heavy or greasy finish. Size: 30 mL / 1.01 fl oz. Suitable for most skin types.
Key Benefits
Helps calm the appearance of redness caused by dryness
Softens the look of post-spot marks
Visibly smooths uneven-looking texture
Helps balance excess oil and shine
Provides lightweight, lasting hydration
Supports a clearer, more refined-looking complexion
How to Use
After cleansing and toning, apply 2–3 drops evenly across the face, avoiding the eye and lip areas. Gently press into the skin until absorbed, then follow with moisturizer. Begin 2–3 times per week, preferably in the evening, and increase gradually. For daytime use, finish with a broad-spectrum sunscreen. Patch testing is recommended before first use.
Guaranteed Support
Your satisfaction is our priority. If you have any questions or concerns, our support team is here to help every step of the way. If something isn't right with your order, we'll make it right - whether that means a replacement, refund, or personalized assistance.
Need Help?
Frequently Asked Questions
What does it help with?
It helps calm redness caused by dryness, soften the look of post-spot marks, refine uneven texture, and support a clearer complexion.
How often should I use it?
Start with 2–3 evenings a week. As your skin adjusts, gradually increase based on tolerance.
Is it suitable for sensitive skin?
It contains soothing, hydrating ingredients, but 16% azelaic acid is a concentrated strength. Patch test and introduce it gradually.
Can I use it during the day?
Yes — morning or evening. When using it during the day, always finish with a broad-spectrum sunscreen.



